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Responsive Mode Research Grants:

The research grant is designed to be flexible enough to support a very wide range of research needs. It is therefore our main scheme for supporting biomedical science in UK universities and NHS Trusts.

MRC research grants are suitable for focused research projects that may be short- or long-term in nature. In addition, they can be used to support method development or development and continuation of research facilities and may involve more than one research group or institution. A research grant can be awarded for any period of up to five years, but those of two years or less are for proof of principle or pilot work only. Applications seeking support of greater than three years should provide a clear justification as to why a longer timescale is needed, for example due to specific research deliverables, or the need for prolonged data collection or follow-up. The budget for research grant awards will not typically exceed £1 million.

Research grants do not cover programmatic approaches or research involving randomised trials of clinical treatments. If your proposed research will lead directly to a separately funded clinical trial, please contact an MRC research board manager to discuss its eligibility.

Further information:  http://www.mrc.ac.uk/Fundingopportunities/Grants/Researchgrant/MRC001730

Deadlines:  Application deadlines are usually in January, May and September. All proposals are assessed by external experts before they are considered by the MRC research boards at their meetings in May/June, October/November and February/March.

Further information on deadlines::  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

 

New Investigator Research Grant (NIRG):

The New Investigator Research Grant (NIRG) is aimed at researchers who are capable of becoming independent principal investigators and who are now ready to take the next step towards that goal.

The scheme can provide talented early-career scientists with a route into a principal investigator position and is aimed at senior post-docs or individuals near the start of their first lectureship. For those who already have an institutional post it provides funding and ‘protected time’ with which to establish an independent research career. A NIRG is also a potential source of research funding for fellows whose awards only cover a personal salary and/or limited research funds.

NIRGs provide funding for three or more years . They are not renewable and cannot usually be extended.

The scheme does not cover research involving randomised trials of clinical treatments. If your proposed research will lead directly to a separately funded clinical trial, you will need to contact an MRC Programme Manager to discuss your eligibility.

NIRG applications can be submitted to any of the 4 Research Boards MCMB, IIB, PSMB, NMHB and Methodology Research Panel (MRP) in parallel with responsive mode applications.

 Further information: http://www.mrc.ac.uk/Fundingopportunities/Grants/NIRG/MRC001733#P57_6292

Deadlines: Application deadlines are usually in January, May and September. All proposals are assessed by external experts before they are considered by the MRC research boards at their meetings in May/June, October/November and February/March.

Further information on deadlines::  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

 

Programme Grants:

Programme Grants provide larger, longer term (five years) and renewable programme funding. They aim to help the medical science community to ‘think bigger’. A programme is defined as a coordinated and coherent group of related projects, which may be developed to address an inter-related set of questions across a broad scientific area. The expectation is that not all the questions will necessarily be answered within the tenure of the award. Parts of the programme may well be a continuation of current activity; however, other elements should be innovative and ambitious. Programmes are a substantial investment for the MRC so due consideration to MRC strategy should also be evident. 

• The standard for Programme Grants is extremely competitive and it is important that applicants discuss their proposals with appropriate staff at MRC Head Office. You must contact the Programme Manager of the relevant MRC Research Board to confirm whether your application fits the scheme - this mandatory step, applies to all new Programme Grant applications (not renewals) and must be completed at least 6 weeks before the submission deadline. Please note that outline applications are no longer necessary. New applications should include a cover letter that confirms the name of the Programme Manager that agreed that an application could be submitted; for renewals the cover letter should confirm the details of the original award.

• When contacting the Programme Manager we ask that you send the following by email:

    • Case: max. 2 pages
    • Resources: please provide a high level indication of the likely cost to the MRC
    • CV for lead and co-investigators: max. 2 pages, plus 1 page for key publications

Further information:  http://www.mrc.ac.uk/Fundingopportunities/Grants/Programmegrant/MRC004804

Deadlines:  Applications are considered in parallel with responsive mode research grants. Application deadlines are usually in January, May and September. All proposals are assessed by external experts before they are considered by the MRC research boards at their meetings in May/June, October/November and February/March.

Further information on deadlines::  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

 

 MRC Industry Collaboration Agreement (MICA)

Any research proposal involving a collaboration with one or more industrial partners (contributing either in cash or in kind) is handled by MRC as a MICA. MICA is not a scheme in itself, but a mechanism to support the establishment of an agreement between academic and industry research partners, which can be applied to the majority of MRC’s funding schemes and calls (to find out if you can apply a MICA to your proposal, please refer to your specific scheme or call). MICA facilitates collaboration as it allows partners to work out and clearly specify arrangements for relative responsibilities, governance, regulatory approvals, indemnity, intellectual property rights, reporting, and access to data and samples before a project starts. In addition, MICAs help to establish that proposed collaboration arrangements are eligible under EU State-Aid regulations for MRC funding.

Further Information:  http://www.mrc.ac.uk/Fundingopportunities/Grants/MICA/Specification/MRC005438 

Deadlines: The application deadlines are those of the chosesn funding scheme.  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

  

Biomedical Catalyst: Developmental Pathway Funding Scheme (DPFS):

Therapeutics, Devices and Diagnostics Development

The BMC: DPFS scheme forms part of the MRC’s Translational Research Strategy and supports the translation of fundamental discoveries toward benefits to human health. It funds the pre-clinical development and early clinical testing of novel therapeutics, devices and diagnostics, including “repurposing” of existing therapies.

Where the proposal involves collaboration with one or more industrial partners the applicant will need to submit a MICA form and heads of terms at the full stage, if invited forward.

The BMC: DPFS scheme supports projects whose goals are to improve prevention, diagnosis, prognosis, or treatment of significant health needs, or that focus on developing research tools that increase the efficiency of developing interventions.

Projects supported by the scheme have clearly defined milestones, outcomes and future plans. These help to maximise both the chance of success, and the likelihood of the project attracting the downstream funding, from public or private sources, required to meet its clinical and commercial aims. The funding panels assessing the project will, if necessary, help to develop proposals and suggest enhancements.

The following activities are eligible for support:

  • Developing candidate therapeutic entities (e.g. drug discovery)
  • Pre-clinical testing of novel therapeutic entities
  • Early-phase clinical studies of novel therapeutic entities (phases 1 and 2)
  • “Repurposing” clinical studies – using existing therapies for new indications
  • Developing and testing novel devices
  • Developing and testing diagnostics (including biomarker validation where the intent is for diagnostic use

Further Details:  http://www.mrc.ac.uk/Fundingopportunities/Grants/DPFS/Specification/MRC004553

Deadlines: DPSF is a two stage application process. Application deadlines are usually in March, July and November for consideration by the Panels at meetings in May/June, September/October and January/February respectively.

Further information on deadlines:  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

 

Biomedical Catalyst: Regenerative Medicine Research Committee (RMRC):

 Supports translation of fundamental discoveries toward benefits to human health.

Funds pre-clinical development and early clinical testing of novel regenerative medicine therapies.

Formally the Translational Stem Cell Committee (TSCRC).Forms part of the MRC’s Translational Research Strategy and will help deliver the joint MRC/Technology Strategy Board Biomedical Catalyst in the short term.

The RMRC scheme will consider applications whose goals will advance the pre-clinical and/or early clinical development of regenerative medicine therapies including:

    • Cellular regenerative therapies spanning stem, progenitor and differentiated cells
    • Tissue repair strategies, including small molecule and biologics for the enhancement of endogenous repair
    • Biomaterial interventions which actively engage repair and regeneration processes

 

The Biomedical Catalyst Developmental Pathway Funding Scheme is the RMRC’s sister programme, and will take the lead on proposals developing:

    • Organ transplantation strategies
    • Interventions targeting cancer stem cells
    • Gene therapies
    • Drug screening programmes using stem-cell derived assays to identify interventions that do not stimulate repair/regeneration processes
    • Use of cells to deliver drugs, antibodies, etc

Further information: http://www.mrc.ac.uk/Fundingopportunities/Grants/RMRC/MRC004680#P61_4626

Deadlines:  There is a two stage application process. The MRC will receive outline applications  usually in March, November and July each years around 12 weeks before the RMRC meeting , and will organise reviews by external expert referees. There will be no opportunity to respond to reviewers comments at this stage.

Further information on RMRC deadlines:  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

 

Fellowships: 

Fellowships are personal awards made to talented researchers at key points in their careers. With an MRC fellowship you have your own funding for a challenging research project and an ambitious programme of research training and personal development. 

MRC offers a range of fellowship award schemes covering both clinical and non-clinical researchers.

Further information on the full range of Fellowship Schemes:  http://www.mrc.ac.uk/Fundingopportunities/Fellowships/index.htm

Non-Clinical Fellowships:

Senior non-clinical fellowships: Award for non-clinical researchers of exceptional ability. 
Further information:  http://www.mrc.ac.uk/Fundingopportunities/Fellowships/Non-clinical/Seniornonclinical/MRC001826

Deadlines:  This fellowship competition is held twice a year deadlines usualy April and September. There is no need to submit an outline application. Please refer to the Fellowships schedule for further information on deadlines:  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

Career Development Award
Up to 5 years support for outstanding post-doctoral researchers who wish to consolidate their research skills. 
Further informationhttp://www.mrc.ac.uk/Fundingopportunities/Fellowships/Non-clinical/Careerdevelopmentaward/MRC001825

Deadlines:  This fellowship competition is held twice a year deadlines usually April and September, however applicants may only apply to one CDA competition in any 12 month period. There is no need to submit an outline application. Please refer to the Fellowships schedule for further information on deadlines:  http://www.mrc.ac.uk/Fundingopportunities/Deadlines/index.htm

  

  

  

  

 

  

 

 

  

 

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