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Welcome to the Chemical Characterisation and Analysis Facility (CCAF) wiki space

The Faculty of Science has recently combined the core technologies for Chemical Characterisation under the single organisational structure of the Chemical Characterisation and Analysis Facility (CCAF). These services are available to all researchers at the University of Bath, as well as researchers from other Universities and external companies.

CCAF Introduction presentation 2017 - CCAF intro sessions presentation 2017.pptx


The characterisation tools available include:

Mass Spectrometry

Accurate mass and isotope determination

  • ESI and APCI ionisation available, coupled to a time-of-flight (TOF) analyser. LC-MS service also offered.
  • Analysis of air-sensitive compounds using a glovebox - mass spectrometer combination
  • Analysis of intact and digested protein samples by nanoLC-MS

For Open Access training click here.

NMR Spectroscopy

  • Determination of structure in solution. Spectrometers ranging from 250-500 MHz are available, and a complete range of modern multinuclear experiments can be run.

NMR Spectroscopy in Pharmacy and Pharmacology

NMR Spectroscopy in Chemistry

X-Ray Diffraction

              X-Ray Powder Diffraction (XRPD) - fingerprinting of crystalline powders or crystalline deposits on matrix. Determination whether a sample is crystalline or amorphous.

              Single Crystal X-Ray Diffraction - Full structural characterisation from a suitable single crystal (i.e. shape of molecule, content of molecule, all geometric data, how molecules pack together, intermolecular forces).

Materials Characterisation Techniques

Thermogravimetry with Evolving Gas Analysis (TG-EGA) - Measurement of mass change upon a change in temperature, with detection of evolved species

Microcalorimetry (µDSC) - Measurement of heat exchange in any physical or chemical transformation

Dynamic Mechanical Analysis (DMA) - Measurement of the elastic modulus (Young's modulus) and visco-elastic behaviour of bars or films

Surface & Porosity Analysis - Measurement of BET surface area and pore size distribution of porous solids

Size Exclusion Chromatography (aka GPC) - Determination of the molar mass distribution of polymer chains

Other Techniques

Elemental Analysis (CHN) -  Analysis of a material to determine mass fractions of carbon, hydrogen and nitrogen within the sample.

Differential Scanning Calorimetry (DSC) -  Technique used to determine endothermic or exothermic physical transformations. Widely used to ascertain sample purity and to study polymer curing.

The DReaM (Dynamic Reaction Monitoring) Facility - Reaction monitoring of homogeneous processes, using NMR, MS (liquids and headspace), HPLC and UV.


News and Updates

Linking research outputs to facilities in Pure – researchers who use CCAF managed facilities are encouraged to link their publications in Pure following the seven speedy steps shown here.

For further information on availability and costs, please do not hesitate to contact the service managers direct via the individual service pages linked above, or the Head of CCAF (Dr Anneke Lubben) by email or phone 01225 384173 (x4173).


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